Healthy Weight

Probiotics and collagen improve weight and lipids

Probiotics reduced weight, fat mass

Diet influences weight, but gut microbiota also play an important role. In this study, 59 overweight participants took a placebo or 10 billion colonyforming-units daily of a lactobacillus probiotic combination.


After 12 weeks, those in the probiotics group on average had lost body weight, waist circumference, had healthier body mass index scores, and better gut microbiota balance, compared to the start of the study, while the placebo group deteriorated in all these measures. In obesity, people become less sensitive to two hormones that regulate appetite; leptin and adiponectin, and do not recognize when they have eaten enough food to satisfy hunger. The probiotics group became more sensitive to leptin as these two hormones came back into balance.


Collagen improves lipids, reduces fat mass

Collagen makes up 25 to 30 percent of total body protein, and may improve heart and circulatory health. In this review of 12 clinical trials, 748 overweight participants, aged 24 to 72, with type 2 diabetes, elevated blood pressure, osteoarthritis, or age-related muscle loss, took a placebo or a daily collagen supplement during varying study periods.


Overall, those taking collagen saw an average 2.7 pound decrease in fat mass, 1.49 percent decline in body mass, LDL cholesterol decline by 4.09 mg per deciliter of blood (mg/dL), total cholesterol by 5.28 mg/dL, and triglycerides by 6.51 mg/dL. Systolic blood pressure decreased an average of 5.04 mmHg, and compared to placebo, fasting and long-term average blood sugar levels declined.


Reference: Nutrients; 2022, Vol. 14, nu14122484

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